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In a double stranded RNA form, retroviruses infect a host cell with their genome, and then are reverse transcribed into double stranded DNA, with the DNA then integrated into the home cell genome When integrated into a host genome, a retrovirus is hard to detect and can lay dormant for prolonged periods, having no discernible effect on the hostFig S5B) IFN and IFN were the most upregulated ligand signatures in the Library of Integrated Networkbased Cellular Signatures (LINCS) L1000 datasets (they also overlap;The genome of infectious bursal disease virus (IBDV) strain was found to consist of two segments of doublestranded (ds) RNA which were 3400 bp (MW 6 X 10(6)) and 2900 bp (MW 176 X 10(6)) long, respectively The ds IBDV RNA could be translated, in vitro, only after extensive denaturation The small RNA segment was found to code for a single polypeptide of MW 90K, while the large RNA

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Double-stranded rna genomes can be found in-A telltale sign of viral invasion, doublestranded RNA sounds cellular alarm bells that touch off a firestorm of interferon According to a paper published July 7 in Science Translational Medicine, dsRNAs that arise from nonviral sources, including hexanucleotide expansions in the C9ORF72 gene, can also instigate harmful inflammationDNA is double helix and RNA is single helix because of their functions inside the cell DNA is meant to store genetic information for the tenure of the cell's life and also preserve it for the next generation of cells when it d

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–395 Google Scholar Herring AJ, Bevan EA Viruslike particles associated with the doublestranded RNA species found in killer and sensitive strains of the yeast Saccharomyces cerevisiae J Gen Virol 1974 Mar;Doublestranded RNA (dsRNA) sometimes occurs It is similar to DNA, except thymine is replaced by uracil This type of RNA is found in some viruses When these viruses infect eukaryotic cells, the dsRNA can interfere with normal RNA function and stimulate an interferon response Circular singlestrand RNA (circRNA) has been found in both animals and plants  Double stranded RNA replicates in a semiconservative manner similar to DNA to produce two doublestranded progeny molecules Singlestranded genetic RNA found in some viruses, such as, TMV is called the plus () strand RNA;

DsRNA is very critical in regulation of gene expression at translational level In our system we have specific miRNA (micro RNA) that are somewhat complementary to a specific mRNA and miRNAmRNA binding forms a double stranded molecule that is degraded by our system at a cellular level So in a way it controls the translation of mRNA (s)However, a few mycoviruses exhibit singlestranded RNA (ssRNA), doublestranded DNA (dsDNA), or singlestranded DNA (ssDNA) genomes Based on the mode of replication and the type of genome, the International Committee on Taxonomy of Viruses has divided all currently known mycoviruses into 16 families and an unclassified group The 16 families include sevenAsked in Biology &

Was "doublestranded RNA binding" (GO;Like DNA, RNA is assembled as a chain of nucleotides, but unlike DNA, RNA is found in nature as a single strand folded onto itself, rather than a paired double strandConsequently, repetitive element expression is induced and doublestranded RNA accumulates, contributing to the neurodegeneration seen in patients with c9FTD/ALS Rescuing histone methylation, lamin, and HP1α abnormalities and/or inhibiting abnormal repetitive element expression may represent promising therapeutic strategies for treating c9FTD/ALS !Figure2

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It acts as a template for the synthesis of a complementary minus () strand to yield a doublestranded RNA molecule This doublestranded RNADoublestranded DNA molecule (Questions 116) 11_____ Which structural feature is found in the singlestranded DNA molecule?Catalyzes the hydrolytic deamination of adenosine to inosine in doublestranded RNA (dsRNA) referred to as AtoI RNA editing This may affect gene expression and function in a number of ways that include mRNA translation by changing codons and hence the amino acid sequence of proteins;

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RNA consists of ribose nucleotides (nitrogenous bases appended to a ribose sugar) attached by phosphodiester bonds, forming strands of varying lengths The nitrogenous bases in RNA are adenine, guanine, cytosine, and uracil, which replaces thymine in DNA Read More on This Topic nucleic acid Ribonucleic acid (RNA)Double stranded RNA, also known as dsRNA, usually shows up in viruses and is somewhat unusual In viruses, it is a unique characteristic, and only a small number of viral families exhibit this trait RNA hybridization happens when one RNA strand combines, or hybridizes, with either another RNA strand or a deoxyribonucleic acid (DNA) strandPremRNA splicing by altering splice site recognition sequences;

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In nature, RNA is found as a singlestranded molecule which is folded onto itself mRNA is the singlestranded RNA molecule which translates into a protein on ribosomes Many viruses have RNA genomes Some viruses have ssRNA genomes while some viruses possess dsRNA genomes dsRNA has two complementary RNA strands paired together Positive sense ssRNAArenavirus RNA genomes are initiated by a prime and realign mechanism, such that the initiating GTP is found as a single unpaired (overhanging) nucleotide when the complementary genome ends anneal to form doublestranded (ds) RNA panhandle structures dsRNAs modeled on these structures do not induce interferon (IFN), as opposed to bluntended (5' ppp)dsRNARNA interference (RNAi) is a posttranscriptional gene silencing mechanism through which targeted genes are silenced by the introduction of doublestranded RNA (dsRNA) into living cells or organisms (Fire et al, 1998)Direct injection and oral delivery/feeding of dsRNA are the main methods used to initiate RNAi in insects, as demonstrated in Lepidoptera (Turner et al, 06),

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The dsRBD domain is also known as DSRM (DoubleStranded RNAbinding Motif) dsRBD proteins are mainly involved in posttranscriptional gene regulation, for example by preventing the expression of proteins or by mediating RNAs localization This domain is also found in RNA editing proteins Interaction of the dsRBD with RNA is unlikely to involve the recognition of specific sequences 4,In a double stranded RNA form, retroviruses infect a host cell with their genome, and then are reverse transcribed into double stranded DNA, with the DNA then integrated into the home cell genome When integrated into a host genome, a retrovirus is hard to detect and can lay dormant for prolonged periods, having no discernible effect on the hostTolllike receptor3 (TLR3), a member of the pathogen recognition receptor family, has been reported to activate immune response and

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For comparisons of sense, antisense, and doublestranded RNA activity, equal masses of RNA were injected (that is, dsRNA was used at half the molar concentration of the single strands) Numbers ofMicrobiology by Sheila A) This enzyme is coded for by a gene in the host cell B) The enzyme probably came from the hostRetrovirus is an RNA virus They insert a copy of their genome into the DNA of host cells In its doublestranded RNA form, which then reverses transcribed into doublestranded DNA, and then gradually inserted into host cell The correct answer is B

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Doublestranded DNA and RNA, and DNA/RNA hybrids form naturally in cells between two nucleic acid strands containing complementary sequences However, these doublestranded nucleic acid structures need to be separated for DNA replication, RNADNA is amazing!!You guys can get in touch with me here and also ask your doubtshttps//wwwinstagramcom/seal_1school/?hl=enPray to God and Stay happy everyIn recent years a great number of doublestranded RNAs have been detected in different viruses

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A) It can have a negativelycharged backbone composed of nitrogenous bases b) Each 3',5'phosphodiester bond will contain one phosphate groupA newlydiscovered doublestranded RNA virus which infects animal cells is found to contain a unique enzyme which synthesizes doublestranded RNA using an RNA template Which of the following statements is likely to be true?Using Enrichr, a Webbased tool for gene set enrichment analysis , we found that the most upregulated GO Molecular Function was "doublestranded RNA binding" (GO;

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The replication of poxvirus is unusual for a virus with doublestranded DNA genome (dsDNA) because it occurs in the cytoplasm, although this is typical of other large DNA viruses Poxvirus encodes its own machinery for genome transcription, a DNA dependent RNA polymerase, which makes replication in the cytoplasm possible Most dsDNA viruses require the host cell's DNAdependent RNAUnlike DNA, RNA is singlestranded An RNA strand has a backbone made of alternating sugar (ribose) and phosphate groups Attached to each sugar is one of four basesadenine (A), uracil (U), cytosine , or guanine (G) Different types of RNA exist in the cell messenger RNA (mRNA), ribosomal RNA (rRNA), and transfer RNA (tRNA) More recently, some small RNAs have been foundFig S5B) IFNγ and IFNα were the most upregulated ligand signatures in the Library of Integrated Networkbased Cellular Signatures (LINCS) L1000 datasets (they also overlap;

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RNA differs from DNA in the following ways RNA is single stranded while DNA is double stranded RNA has a sugar called ribose while DNA has a sugar called deoxyribose RNA has the base uracilFig S5C and tables S2 and S3) These data are consistent with prior RNAseq analyses (4) of frontal lobes of the same patients that foundRNA pseudoknots are found in virtually all classes of RNA and play key roles in a variety of biological processes They often constitute a local structural element that may act as a recognition site for proteins involved in replication initiation or translational regulation ()The formation of most functional pseudoknots involves WatsonCrick base pairing of residues in an RNA

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Wickner RB Doublestranded RNA replication in yeast the killer system Annu Rev Biochem 1986;RNA interference (RNAi) is a genetic regulatory system that functions to silence the activity of specific genes RNAi occurs naturally, through the production of nuclearencoded premicroRNA (premiRNA), and can be induced experimentally, using short segments of synthetic doublestranded RNA (dsRNA)About Us Terms and Conditions;

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The structures of RNA and DNA are almost identical, so there is no reason why you can't have double stranded RNA Similarly DNA can be single stranded In fact, for DNA replication and transcription, the DNA strands must be separated dsRNA and ssDNA are most commonly found inThe birth of long noncoding RNAs (lncRNAs) is closely associated with the presence and activation of repetitive elements in the genome The transcription of endogenous retroviruses as well as long and short interspersed elements is not only essential for evolving lncRNAs but is also a significant source of doublestranded RNA (dsRNA)

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